Titriplex Decalcifying substance

From:louise renton

Tritiplex is a "brand" name for an EDTA(ethylene diamine tetra acetic acid) 
salt. If I recall, this substance acts as a chelating agent - atttracting Ca 
molecules and complexing with them. The use of such as agent is that it is 
gentler on the tissues, but markedly slower than some of the acidic agents.
Hope this helps, i am sure that some of the more chemistry inclined 
histonetters will be able to expand on my simplified explanation.

Best regards

Louise Renton
Bone Research Unit
MRC
Johannesburg
South Africa
Tel & fax +27 11 717 2298
"Time flies like an arrow, fruit flies like a banana"





>From: Patsy Ruegg 
>To: case.sinclair@imvs.sa.gov.au, histonet@pathology.swmed.edu
>Subject: Re: Advice on use of Titriplex Decalcifying substance
>Date: Wed, 04 Dec 2002 12:47:49 -0700
>
>never heard of Titriplex.
>patsy
>
>
>
>Patsy Ruegg, HT(ASCP)QIHC
>IHCtech, LLC
>Fitzsimmons BioScience Park
>12635 Montview Blvd. Suite 216
>Aurora, CO 80010
>P-270-859-4060
>F-270-859-4110
>HP-303-644-4538
>HF-303-644-3377
>hm email pruegg@msn.com
>wk email pruegg@colobio.com
>
>
>
>
>
>>From: Case 
>>To: HistoNet Server 
>>Subject: Advice on use of Titriplex Decalcifying substance
>>Date: Wed, 04 Dec 2002 15:25:28 +1030
>>
>>Hi All,
>>  My boss would like to know if Titriplex (manufacturer unknown..maybe 
>>Merck)
>>is a acid decalcifying substance or not?
>>
>>Any information greatly appreciated,
>>
>>Regards,
>>
>>Case Sinclair
>>
>>on Behalf of :
>>Dr Rob Moore
>>Adelaide Centre for Spinal Research
>>IMVS
>>Frome Road
>>Adelaide
>>SA  5001
>>AUSTRALIA
>
>
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