Dr. Ian Montgomery at the University of Glasgow, Scotland asks:

>>Actinic keratosis: Fix and process as usual for skin or does this condition 
require a more specialized technique. My usual for skin would be formalin 
then alcohol / amyl acetate dehydration.<<

Usual technique for skin would work fine for most actinic keratoses and 
seborrheic keratoses. Occasionally actinic keratoses are covered by a thick 
mass of keratin ("cutaneous horn") which if it doesn't fall off in the course 
of grossing the specimen may render microtomy somewhat more challenging.

Bob Richmond
Samurai Pathologist
Knoxville, Tennessee USA