RE: [Histonet] puzzling morphology
From: | "Rogerson Kemlo (ELHT) Pathology" |
It's not actually an absence of tissue is it? The spaces could be due to
virus, like koilocytotic atypia. It could also be an artefact as you
suggest but I can't figure what could cause perinuclear haloing as you
suggest, I would have thought cellular changes would have affected the
whole cell not just shrinking the nucleus.
-----Original Message-----
From: histonet-bounces@lists.utsouthwestern.edu
[mailto:histonet-bounces@lists.utsouthwestern.edu] On Behalf Of Walters,
Katherine S
Sent: 23 August 2005 22:53
To: histonet@pathology.swmed.edu
Subject: [Histonet] puzzling morphology
I am once again in need of some collective wisdom from the experts.
I have some paraffin embedded lung tissue in which the bronchial
endothelium cells exhibit "spaces" (around the nucleus) in the cytoplasm
in the H&E 5 micron section. These were fixed with zinc formalin.
Does anyone know what would cause this absence of tissue?
Thanks again for your wisdom,
Kathy
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