RE: CK-7 in sarcomas
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From: | "Nader, Alexander" <alexander.nader@wgkk.sozvers.at> |
To: | 'Richard Cartun' <Rcartun@harthosp.org>, Histonet <Histonet@pathology.swmed.edu> |
Reply-To: | |
Content-Type: | text/plain |
> -----Original Message-----
> From: Richard Cartun [mailto:Rcartun@harthosp.org]
> Sent: Thursday, August 10, 2000 11:16 PM
> To: Histonet
> Subject: CK-7 in sarcomas
>
>
> I have seen cytokeratin-7 (CK-7) in myofibroblasts, but has
> anyone seen CK-7 immunoreactivity in "true" sarcomas?
I never tried it, but I wouldn't be too impressed if CK-7 is expressed on
some angiosarcomas as these tumors very often are - at least focally-
positive for "epithelial" markers.
Take also a look at:
Smith TA, Machen SK, Fisher C, Goldblum JR. Usefulness of cytokeratin
subsets for distinguishing monophasic synovial sarcoma from malignant
peripheral nerve sheath tumor.
Am J Clin Pathol 1999 Nov;112:641-8.
Alexander Nader
PS: Although it's a litle bit off-topic: but what's a "true" sarcoma?
Coming from developmental biology to pathology I always wondered why renal
cell tumors are called "carcinomas"!
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