Re: Mast cell control tissues
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From: | Tim Morken <timcdc@hotmail.com> |
To: | Histonet@Pathology.swmed.edu |
Reply-To: | |
Date: | Thu, 08 Apr 1999 08:14:19 -0400 (EDT) |
Content-Type: | text/plain |
Mast cells are found primarily in the connective tissue of the skin
and mucous membranes. They are also found in the thymus and the
capsules of most organs. Look around small blood vessels. There are
none in the CNS. The location gives a hint of their function:
protection against foriegn elements through quick distribution of
chemicals which help eliminate those elements.
Mast cells are part of the immune system and are reactive to
antibodies produced by plasma cells against foriegn elements. The
granules in mast cells contain histamine (dialates blood vessels
allowing more blood to the affected area) and heparin (prevents blood
clotting allowing flushing of tissue), among other things. When you
take an anti-histamine you are using a drug that blocks receptors on
mast cells and prevents their activation.
Those who are allergic to bees and other stinging insects have a
super-sensitve mast cell system which all release their contents at
once causing anaphylaxis.
Tim Morken, B.A., EMT(MSA), HTL(ASCP)
Infectious Disease Pathology
Centers for Disease Control
MS-G32
1600 Clifton Rd.
Atlanta, GA 30333
USA
email: tim9@cdc.gov
timcdc@hotmail.com
FAX: (404)639-3043
----Original Message Follows----
From: AEJNSN@aol.com
To: Histonet@pathology.swmed.edu
Subject: Mast cell control
Date: Wed, 07 Apr 1999 18:16:49 -0400 (EDT)
We are looking for a mast cell control. In any of the literature I
read it
says any tissue with mast cells in it should work..wel the problem is
finding
tissue. Please do not laugh at such a question but does anyone have
any
suggestions as to specific tissue that contains mast cells? Thank you
for
your help.
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