Re: Mast cell controls and CNS

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From:Geoff McAuliffe <mcauliff@UMDNJ.EDU>
Date:Thu, 08 Apr 1999 11:44:37 -0400
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Tim Morken wrote:

> Mast cells are found primarily in the connective tissue of the skin
> and mucous membranes. They are also found in the thymus and the
> capsules of most organs. Look around small blood vessels. There are
> none in the CNS.

    I beg to differ. Try Silver et al., 1996, Trends in
Neuroscience19:25-31; "Mast cells in the brain: evidence and functional
    Also, there are mast cells in the meninges. Dimlich et al. 1991, J.
Neurocytology 485-503,  "Linear arrays of homogenous mast cells in the
dura mater of the rat".

The other comments are right on.

Geoff McAuliffe, Ph.D.
Neuroscience and Cell Biology
Robert Wood Johnson Medical School
675 Hoes Lane, Piscataway, NJ 08854
voice: (732)-235-4583; fax: -4029

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