RE: [Histonet] universal negative control

From:"Sebree Linda A."


We use the Universal Negative Control from Biocare and use it exactly
how you describe.  Our director and supervisor both seemed to think this
would "fly".  We have been inspected since that change but I'm not sure
the topic came up.

Linda Sebree, HT(ASCP)
University of Wisconsin Hospital & Clinics
IHC/ISH Laboratory
600 Highland Ave.
Madison, WI 53792
FAX: (608)262-7174

-----Original Message-----
[] On Behalf Of Michele
Sent: Thursday, April 17, 2008 1:35 PM
Subject: [Histonet] universal negative control

Does anyone know if it is acceptable to include just one "Universal"
negative control with patient slides on which both polyclonal and
monoclonal antibodies are being run? A previous manager (previous is the
key word here) made us change all staining protocols to include only one
universal control (I believe it was from Biocare) for each patient, no
matter what antibodies were being tested on that patient, in a supposed
effort to cut down on slide costs. 

Would this fly in a CAP inspection? 

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