[Histonet] Nuclear bubbling in rapid processed biopsies

From:"Cazares, Ruth"

Hi all,


I have a question for those using rapid biopsy programs.  How long does
the biopsy fix in formalin before starting the program? ( I'm interested
in the ones that come in during the work day and obviously not the one
that have sat in formalin overnight). Is there a minimum time for good
results?  Does anyone see bubbling of the nucleus in these rapid
processed samples?  I too am trying to modify the way we do things in
our lab to accommodate the workload increase, but occasionally I see
nuclear bubbling.  Any thoughts, ideas or suggestions?  


Ruth Cazares


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