We tried measuring the "blood" pressure generated by our perfusion
techniques but were unsuccessful. Back to calculating blood volumes,
blood circulation times (using formulas from vetinarian school documents).
A 35 g mouse, has a blood volume of 1.75 - 2.4 ml (blood volume=
50-80ml/kg) physiological blood flow rates are 6.3 - 8.7 ml/min and
systolic blood pressure of 113 mm Hg.
Our perfusion rate of 2 ml/min is therefore much lower than physiological
What maximum rates have been used in your experiments (without exploding
the cardiovascular system)?
B.P. 37 Labége Innopole
31676 LABEGE CEDEX FRANCE
tel : (33)561004179 fax :(33)561004001
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