Re: Breast specimens

From:rueggp

I am still wondering about the issue of enhancing formalin fixation with MW for
Her2, has this been addressed by the companies selling FDA approved tests?
Patsy

Bryan Hewlett wrote:

> Bob,
>
> The fixation time in NBF for the Herceptest is 16-24 hours.
> As you say, a good thing too!
>
> Bryan
>
> Bryan R. Hewlett
> Technical Specialist
> Department of Anatomical Pathology
> Hamilton Regional Laboratory Medicine Program.
> Ontario, Canada
> ----- Original Message -----
> From: 
> To: 
> Sent: Thursday, April 25, 2002 5:02 PM
> Subject: Re: Breast specimens
>
> > Donna Willis responds:
> >
> > >>Since we use HER2/neu in our lab as an ASR, I have done a little more
> > research on the formalin fixation and you are correct. The Herceptest and
> > Pathway package inserts/protocols are very detailed about the amount of
> time
> > that a sample must be formalin fixed.<<
> >
> > What is the amount of time the specimen must be left in formalin? Does the
> > amount of time demand overnight fixation? Good thing if it did.
> >
> > What's an ASR?
> >
> > Bob Richmond
> > Samurai Pathologist
> > Knoxville TN
> >





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