Re: Breast specimens
Donna Willis, Histology Lab Manager, Harris Methodist, Fort Worth, Texas
notes:
>>When using the FDA approved DAKO Herceptest [for HER2/neu,] or the FDA
Ventana Pathway method, you have to use formalin as the fixative. - In our
lab we make sure the specimen is fixed properly by using microwave technology
before the samples are placed on the tissue processor.<<
I'm not sure it makes any difference, but microwaving is a form of fixation,
and could be considered an irregular fixation method for the FDA approved
test. I'd at least want to run some samples in parallel to find out if it
alters the results. Remember always that the USA has 5% of the world's
population and 75% of its lawyers...
Bob Richmond
Samurai Pathologist
Knoxville TN
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