RE: Collagen Stains??
The annulus fibrosus contains both type I and type II collagen; nucleus
pulposus is reputed to contain mostly collagen II with a little collagen I
around the edge.
Allen A. Smith, Ph.D.
School of Graduate Medical Sciences
Podiatric Medicine and Surgery
Miami Shores, Florida 33161-6695
From: Boneslides@aol.com [mailto:Boneslides@aol.com]
Sent: Thursday, April 18, 2002 4:31 PM
Subject: Collagen Stains??
Can anyone recommend a stain that will differentiate different types of
fibro-cartilage? I am trying to differentiate the nucleus pulposis from
annulus fibrosis in spine sections. My understanding (which is VERY
limited!!!) is that one is made of Type I collagen and the other is Type II
Any help will be greatly appreciated!
Orthopedic Pathology and Biomaterials Laboratory
The Cleveland Clinic Doundation
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