RE: Collagen Stains??

From:"Monson, Frederick C."

Is this the same 'nucleus pulposus' that I was taught to treat as a remnant
of the notochord?  If so, then perhaps there is another literature source to
plumb, at least for the parts that have not been totally converted.


Fred Monson

> ----------
> From:
> Sent: 	Thursday, April 18, 2002 4:30 PM
> To:
> Subject: 	Collagen Stains??
> Can anyone recommend a stain that will differentiate different types of 
> fibro-cartilage?  I am trying to differentiate the nucleus pulposis from 
> annulus fibrosis in spine sections.  My understanding (which is VERY 
> limited!!!) is that one is made of Type I collagen and the other is Type
> II 
> collagen.
> Any help will be greatly appreciated!
> Thanks!
> Diane Mahovlic
> Orthopedic Pathology and Biomaterials Laboratory
> The Cleveland Clinic Doundation
> Cleveland, Ohio

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