Microchatter got you down? Face, chill on ice, section the block slowly and
evenly while breathing hot breath on the block face (like trying to fog a
mirror). Also, use plain old Paraplast. I have enough to do without worrying
whether I am mistreating or offending the mystery polymers and plasticizers
in some newfangled embedding medium. When I switched back to Paraplast from
one of those s0-called improved mixtures, all microtomy problems in my lab
disappeared. Just my opinion and experience.
Jeff Silverman HT HTL QIHC (ASCP)
Southside Hospital
Bay Shore NY USA