Morning Barbara,
	The answer to your question lies in a relatively new microarray
process which involves micro-derivatized glass (beads or slides).  Search
Google for "derivatized glass".  There is a paper with a specific answer for
your question at:
http://www-schreiber.chem.harvard.edu/home/pdffiles/jacs1999vol_p_.pdf.  I
can forward the PDF if you do not have it.  You can find details of the
method at:  http://www-schreiber.chem.harvard.edu/home/protocols/SMP.html.

Hope this helps,

Fred Monson

Frederick C. Monson, PhD   
Center for Advanced Scientific Imaging
Schmucker II Science Center
West Chester University
South Church Street 
West Chester, Pennsylvania, USA, 19383
Phone:  610-738-0437
FAX:  610-738-0437
fmonson@wcupa.edu
CASI URL:  http://darwin/wcupa.edu/casi/
WCUPA URL:  http://www.wcupa.edu/
Visitors URL:  http://www.wcupa.edu/_visitors/

> ----------
> From: 	Barbara Stancel
> Sent: 	Tuesday, April 2, 2002 7:47 PM
> To: 	histonet@pathology.swmed.edu
> Subject: 	Microarray Question
> 
> Dear Histonetters,   I am asking this question for one of our pathologists
> who is working on a special project. His question, "I need to efficiently
> bind 5'amine modified oligonucleotides to coated microscope slides.  What
> would be the best coating?"       I will pass along all the information
> you send.....but if you need more specific information/questions, give me
> some time to catch him!
> Histologically yours,
> 
> Barbara H. Stancel, HTL(ASCP)HT
> USDA, FSIS, OPHS, Eastern Laboratory, Pathology
> RRC, 950 College Station Road                          &nbs 
> 
>   _____  
> 
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>