Thoughts on Chloroform

From:Connie McManus <conmac@cc.usu.edu>

> I'm sure the Pop-Tart I had for breakfast wasn't good for me either.  Lets
> face it most of the chemicals we use (including water) will eventually be
> listed as hazardous.  Each time we boot a beloved chemical out our job
> becomes just a little harder.  Besides I think the Chloroform smells neat.
> (strickly a personal opinion.....)

> Charles R. Embrey Jr., PA(AAPA), HT(ASCP)
> Histology Supervisor

Amen, Charles! Not to mention that even getting out of bed poses hazards
and risk!  

I have been  exposed to everything you can think of and whatever damage
that can possibly be done to me has been done. I fully expect to be
diagnosed with cancer some day, so I keep a careful watch for it...
early detection is the best thing I can do for myself. So I don't get
excited about things anymore.  However, I am not so cavalier about it as
this may sound.  I take safety very seriously and take all the required
precautions with all chemicals, regardless of how minimal their toxicity
because there is always that chance I won't develop cancer and I
certainly don't want to track it home or expose someone else to it.  And
because it's the rules we have to live by.   With all the safety
apparel, fume hoods, etc. I doubt the amount of exposure a person would
get over a lifetime of working in a lab and making Carnoy's or other
chloroform containing solutions, isn't going to get you to that limit. 
Sorry, Terry, I mean no disrespect to you, but I think your remark about
chloroform being one for the history books is a bit over reactionary. 
Would you like to further support your comments?  I'm sure you had a
very good reason for stating them.  I'm all ears (eyes?).  *g*    

> I'm sure the Pop-Tart I had for breakfast wasn't good for me either. 

No doubt!  all that fat and sugar... man, you're going to develop a
heart condition, diabetes, colon cancer,... We could generate a
neverending list of things, eh?  *VVBG*

> Lets
> face it most of the chemicals we use (including water) will eventually be
> listed as hazardous.  

Believe it or not, I saw an MSDS on water.  It said something to the
effect that it was fatal if inhaled.  Does the word "duh" mean anything
here?? *g*

>  Besides I think the Chloroform smells neat.
> (strickly a personal opinion.....)
EWWWW! No thanks!  By 3PM I'm nearly brain dead as it is. I can't
imagine the drive home after sniffing chloroform!  Oh, well, to each 
his own! *g*

Connie McManus


 
> Charles R. Embrey Jr., PA(AAPA), HT(ASCP)
> Histology Supervisor
> Carle Clinic
> Urbana, IL
> 
> -----Original Message-----
> From: t.hacker@har.mrc.ac.uk [mailto:T.Hacker@har.mrc.ac.uk]
> Sent: Tuesday, April 24, 2001 3:13 AM
> To: Charles.Embrey
> Cc: 'Histonet'
> Subject: RE: lymph node revealing solution
> 
> Date sent:              Mon, 23 Apr 2001 15:59:06 -0500
> From:                   "Charles.Embrey" <Charles.Embrey@carle.com>
> Subject:                RE: lymph node revealing solution
> To:                     "'LINDA GORMAN'" <lgorman1@kumc.edu>
> Copies to:              "'Histonet@pathology.swmed.edu'"
> <Histonet@pathology.swmed.edu>
> 
> > Linda's right.  It's the real (original) Carnoy's Fix.  I use it and it's
> > great:
> > Acetic Acid   10ml
> > 100% ETOH     60ml
> > Chloroform    30ml
> Carle Clinic
> > Urbana, IL
> >
> 
> I am sure it is, but you should seriously consider finding an
> alternative to using chloroform. This is a suspect carcinogen in
> man and really should not be used. I wouldn't like to see this
> fixative come back into general use, and as with mercury
> containing fixatives,should be one for the history books.
> Terry Hacker,
> Medical Research Council,
> Harwell,
> Didcot,
> Oxfordshire, OX11 ORD
> 01235 834393 x360

-- 
ࡱ



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