Bone Labeling of Animals

From:"Bobst, John" <>

I am currently doing study on spine fusion in a bovine model.  We are
looking at fusion rates and bone growth.  Therefore, we are going to do 4
different bone labels: oxytetracycline, alizarin complex, fluoroscein, and
xylenol orange.  Has anyone ever heard of any side effects of xylenol orange
or any of the others?  I have heard that the animals could present a color
similar to the dye for a short time following injection.


John A. Bobst

Research Assistant II
University of Iowa
Bone Healing Research Laboratory
Iowa City, Iowa

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